研究成果 (*: 通訊作者)
更新日期:2013年10月3日
Full Papers
1. Liu, B. Y., T. L. Tsai, C. Y. Ho, S. H. Lu, C. J. Lai †*, Y. R. Kou †*. (2013) Role of TRPA1 and TRPV1 in the ROS-dependent sensory irritation of superior laryngeal capsaicin-sensitive afferents by cigarette smoke in anesthetized rats. Pulm Pharmacol Ther 26:364-372. (†denotes equal contribution as co-corresponding author) SCI; NSC 101-2320-B-010-042-MY3.
2. Lin, Y. J., Y. S. Lin, C. J. Lai, Z. F. Yuan, T. Ruan, and Y. R. Kou*. (2012) Perivagal antagonist treatment in rats selectively blocks the reflex and afferent responses of vagal lung C-fibers to intravenous agonists. J Appl Physiol 114: 361-370. SCI; NSC 101-2320-B-010-042-MY3 and NSC 98-2628-B-040-011-MY3
3. Shen, M. Y., Y. L. Luo, C. H. Yang, T. Ruan, and C. J. Lai*. (2012) Hypersensitivity of lung vagal C fibers induced by acute intermittent hypoxia in rats: role of reactive oxygen species and TRPA1. Am J Physiol Regul Integr Comp Physiol 303: R1175-R1185. SCI; NSC97-2320-B-320-004 and NSC98-2628-B-320-003-MY3.
4. Wang, Y. C., C. Y. Chen, T. B. J. Kuo, C. J. Lai, and C. C. H. Yang*. (2012) Influence of antipsychotic agents on heart rate variability in male WKY rats: implications for cardiovascular safety. Neuropsychobiology 65: 216-226.
5. Chen, T. I., C. J. Lai, C. J. Hsieh, K. L. Tsai, and K. T. Yang*. (2011) Differences in left ventricular cardiomyocyte loss induced by chronic intermittent hypoxia between spontaneously hypertensive and Wistar-Kyoto rats. Sleep Breath 15: 845-854. SCI; NSC-96-2320-B-320-017-MY2.
6. Lai, P. C., Y. T. Huang, C. C. Wu, C. J. Lai, P. J. Wang, T. H. Chiu*. (2011) Ceftriaxone attenuates hypoxic-ischemic brain injury in neonatal rats. J Biomed Sci 18: 69-78. SCI
7. Huang, Y. M., C. C. H. Yang, C. J. Lai, and T. B. J. Kuo*. (2011) The influence of autonomic interventions on the sleep-wake-related changes in gastric myoelectrical activity in rats. Neurogastroenterol Motil 23: 560-e208. SCI; NSC-98-2314-B-010-022.
8. Kuo, T. B. J., Z. F. Yuan, Y. S. Lin, Y. N. Lin, W. S. Li, C. C. H. Yang, and C. J. Lai*. (2011) Reactive oxygen species are the cause of the enhanced cardiorespiratory response induced by intermittent hypoxia in conscious rats. Respir Physiol Neurobiol 175: 70-79. SCI; NSC-97-2320-B-320-004 and NSC-98-2628-B-320-003-MY3.
9. Huang, Y. M., C. C. H. Yang, C. J. Lai, and T. B. J. Kuo*. (2010) Involvement of sympathetic function in the sleep-related change of gastric myoelectrical activity in rats. J Sleep Res 19: 192-200. SCI
10. Kuo, Y. L. and C. J. Lai*. (2008) Ovalbumin sensitization enhances the sensitivity of pulmonary C-fiber afferents in Brown Norway rats. J Appl Physiol 105: 611-620. SCI; NSC-92-2320-B-320-022 and NSC-93-2320-B-320-011.
11. Kuo, T. B. J., F.-Z. Shaw, C. J. Lai, and C. C. H. Yang*. (2008) Asymmetry in sympathetic and vagal activities during sleep-wake transitions. Sleep 31: 311-320. SCI; NSC-94-2314-B-010-076.
12. Lai, C. J., C. C. H. Yang, Y. Y. Hsu, Y. N. Lin, and T. B. J. Kuo*. (2006) Enhanced sympathetic outflow and decreased baroreflex sensitivity are associated with intermittent hypoxia-induced systemic hypertension in conscious rats. J Appl Physiol 100: 1974-1982. SCI; NSC-94-2320-B-320-007.
13. Sun, T. B., C. C. H. Yang, C. J. Lai, and T. B. J. Kuo*. (2006) Time course of cardiovascular neural regulation during programmed 20-sec apnea in rats. Crit Care Med 34: 765-770. SCI; NSC-92-2314-B-303-013.
14. Kuo, T. B. J.,†C. J. Lai,†Y. T. Huang, and C. C. H. Yang*. (2005) Regression analysis between heart rate variability and baroreflex-related vagus nerve activity in rats. J Cardiovasc Electrophysiol 16: 864-869. SCI; NSC-93-2320-B-320-008. (†denotes equal contribution as co-first author)
15. Chen, H. Y., T. B. J. Kuo, F.-Z. Shaw, C. J. Lai, and C. C. H. Yang*. (2005) Sleep-related vagotonic effect of zolpidem in rats. Psychopharmacology (Berl) 181: 270-279. SCI; NSC-93-2314-B-320-008.
16. Lai, C. J., T. Ruan, and Y. R. Kou*. (2005) The involvement of hydroxyl radical and cyclooxygenase metabolites in the activation of lung vagal sensory receptors by circulatory endotoxin in rats. J Appl Physiol 98: 620-628. SCI; NSC-92-2320-B-010-025, NSC-92-2320-B-010-038, NSC-91-2320-B-320-005, and NSC-89-2320-B-320-021.
17. Kuo, T. B. J., F.-Z. Shaw, C. J. Lai, C.-W. Lai, and C. C. H. Yang*. (2004) Changes in sleep patterns in spontaneously hypertensive rats. Sleep 27: 406-412. SCI; NSC-90-2745-P320-001 and NSC-91-2320-B320-007.
18. Kuo, T. B. J., C. J. Lai, F.-Z. Shaw, C.-W. Lai, and C. C. H. Yang*. (2004) Sleep-related sympathovagal imbalance in SHR. Am J Physiol Heart Circ Physiol 286: H1170-1176. SCI; NSC-90-2745-P320-001.
19. Yang, C. C. H., F.-Z. Shaw, C. J. Lai, C.-W. Lai, and T. B. J. Kuo*. (2003) Relationship between electroencephalogram slow-wave magnitude and heart rate variability during sleep in rats. Neurosci Lett 336: 21-24. SCI; NSC-89-2745-P320-001 and NSC-89-2320-B320-026.
20. Shaw, F. Z.,* C. J. Lai, and T. H. Chiu. (2002) A low-noise flexible integrated system for recording and analysis of multiple electrical signals during sleep-wake states in rats. J Neurosci Methods 118: 77-87.
21. Lai, C. J., C. Y. Ho and Y. R. Kou*. (2002) Activation of lung vagal sensory receptors by circulatory endotoxin in rats. Life Sci 70: 2125-2138.
22. Lai, C. J. and Y. R. Kou*. (1998) Inhibitory effect of inhaled wood smoke on the discharge of pulmonary stretch receptors in rats. J Appl Physiol 84: 1138-1143.
23. Lai, C. J. and Y. R. Kou*. (1998) Stimulation of pulmonary rapidly adapting receptors by inhaled wood smoke in rats. J Physiol 508: 597-607.
24. Lai, C. J. and Y. R. Kou*. (1998) Stimulation of vagal pulmonary C fibers by inhaled wood smoke in rats. J Appl Physiol 84: 30-36.
25. Yen, S. H., C. J. Lai, J. Y. Lin, and J. T. Pan*. (1997) Inhibitory effect of dopamine on dorsomedial arcuate neurons in rat brain slices: potentiation by coadministration of cocaine. Brain Res Bull 42: 347-3517.
26. Kou, Y. R.*, C. J. Lai, T. H. Hsu, and Y. S. Lin. (1997) Involvement of hydroxyl radical in the immediate ventilatory responses to inhaled wood smoke in rats. Respir Physiol 107: 1-13.
27. Pan, J. T.*, C. J. Lai, and S. H. Yen. (1996) Effects of natriuretic peptides and dopamine on single-unit activity of dorsomedial arcuate neurons in rat brain slices. Brain Res 737: 78-82.
28. Wang, C. Y., C. J. Lai, and Y. R. Kou*. (1996) Inhibitory influence of lung vagal C-fiber afferents on the delayed ventilatory response to inhaled wood smoke in rats. Chinese J Physiol 39: 15-22.
29. Kou, Y. R.*, C. Y. Wang, and C. J. Lai. (1995) Role of vagal afferents in the acute ventilatory responses to inhaled wood smoke in rats. J Appl Physiol 78: 2070-2078.
30. Kou, Y. R.* and C. J. Lai. (1994) Reflex changes in breathing pattern evoked by inhalation of wood smoke in rats. J Appl Physiol 76: 2333-2341.
Conference Abstracts
1. Yang, C. H., Y. R. Kou, M. C. Liang, and C. J. Lai. (2013) Effect of reactive oxygen species on hypersensitivity of lung vagal C fibers induced by intermittent hypoxia in rats. The 12th meeting of the Asia Pacific Federation of Pharmacologists, Shanghai, China.
2. Lin, T. Y. and C. J. Lai. (2013) Effect of intermittent hypoxia on airway hyperresponsiveness in Brown Norway rats. Symposia, the 28th Joint Annual Conference of Biomedical Science, Taipei, Taiwan.
3. Lai, C. J., M. Y. Shen, Y. L. Luo, and C. H. Yang. (2012) Hypersensitivity of lung vagal C fibers induced by acute intermittent hypoxia in rats: role of reactive oxygen species and TRPA1. Experimental Biology 2012, San Diego, USA.
4. Jian, L. Y. and C. J. Lai. (2011) Hypersensitivity of pulmonary chemoreflex induced by exercise: role of reactive oxygen species and cyclooxygenase metabolites. Symposia, the 26th Joint Annual Conference of Biomedical Science, Taipei, Taiwan.
5. Shen, M.-Y., Y.-L. Luo, and C. J. Lai. (2010) Intermittent hypoxia enhances chemical sensitivity of pulmonary C fibers in rats: role of reactive oxygen species. Experimental Biology 2010, Anaheim, USA.
6. Li, W. S., T. B. J. Kuo, C. C. H. Yang, and C. J. Lai. (2010) Effect of N-acetylcysteine on intermittent hypoxia-enhanced cardiorespiratory response in conscious normotensive and hypertensive rats. Symposia, the 25th Joint Annual Conference of Biomedical Science, Taipei, Taiwan.
7. Zhuang, W. L. and C. J. Lai. (2010) Chronic intermittent hypoxia enhances sensitivity of pulmonary C fibers in rats. Symposia, the 25th Joint Annual Conference of Biomedical Science, Taipei, Taiwan.
8. Yuan, Z. F., M.-J. Lin, T. B. J. Kuo, C. C. H. Yang, and C. J. Lai. (2009) Role of superoxide anion in the chemoreflex and cardiovascular responses to chronic intermittent hypoxia in spontaneously hypertensive rats. 36th International Congress of Physiological Sciences, Kyoto, Japan.
9. C.-H. Yang, T. B. J. Kuo, C. C. H. Yang, and C. J. Lai. (2009) Inducible nitric oxide synthase contributes to chronic intermittent hypoxia-induced chemoreflex activation and cardiovascular responses in spontaneously hypertensive rats. Symposia, the 24th Joint Annual Conference of Biomedical Science, Taipei, Taiwan.
10. Lai, C. J., Y.-N. Lin, T. B. J. Kuo, and C. C. H. Yang. (2008) Role of reactive oxygen species in the chemoreflex and cardiovascular responses to intermittent hypoxia in conscious rats. 2008 ATS International Conference, Toronto, Canada.
11. Luo, Y.-L., Y.-J. Chen, and C. J. Lai. (2008) Neuroplasticity of pulmonary C fibers induced by intermittent hypoxia in rats. Symposia, the 23th Joint Annual Conference of Biomedical Science, Taipei, Taiwan.
12. Lin, M.-J., T. B. J. Kuo, C. C. H. Yang, and C. J. Lai. (2008) Exaggerated blood pressure response to intermittent hypoxia is associated with enhanced arterial chemoreflex sensitivity and sympathetic outflow in spontaneously hypertensive rats. The 23th Joint Annual Conference of Biomedical Science, Taipei, Taiwan.
13. Lai, C. J., J.-Z. Deng, C. C. H. Yang, and T. B. J. Kuo (2007) Cardiorespiratory changes evoked by chronic intermittent hypoxia in female rats: role of estrogen. International Brain Research Organization (IBRO) 2007 Congress Satellite Meeting, S11 Physiology and Pathophysiology of the Autonomic Nervous System, Hualien, Taiwan.
14. Deng, J.-Z., C. C. H. Yang, T. B. J. Kuo, and C. J. Lai. (2007) Endogenous sex steroids in the chemoreflex and cardiovascular responses to chronic intermittent hypoxia in conscious rats. The 22th Joint Annual Conference of Biomedical Science, Taipei, Taiwan.
15. Chen, Y.-J., Y.-N. Lin, T. B. J. Kuo, C. C. H. Yang, and C. J. Lai. (2007) Role of hydroxyl radical in the chemoreflex and cardiovascular responses to chronic intermittent hypoxia in conscious rats. The 22th Joint Annual Conference of Biomedical Science, Taipei, Taiwan.
16. Lai, C. J., Y.-N. Lin, T. B. J. Kuo, and C. C. H. Yang. (2006) Intermittent hypoxia enhances chemoreflex sensitivity and sympathetic activity in conscious rats: roles of reactive oxygen species. The Fourth Symposium on Hypoxia across the Strait. The Eighth Chiang Shou-Teh Symposium, Taipei and Hualien, Taiwan.
17. Lin, Y.-N., T. B. J. Kuo, C. C. H. Yang, and C. J. Lai. (2006) Role of superoxide anion in the chemoreflex and cardiovascular responses to chronic intermittent hypoxia in conscious rats. The 21th Joint Annual Conference of Biomedical Science, Taipei, Taiwan.
18. Lai, C. J., C. C. H. Yang, Y. Y. Hsu, and T. B. J. Kuo. (2005) Enhanced sympathetic activity and decreased baroreflex sensitivity are associated with intermittent hypoxia-induced systemic hypertension in conscious rats. 2005 ATS International Conference, San Diego, USA.
19. Kuo, Y. L. and C. J. Lai. (2005) The involvement of pulmonary C fibers in ovalbumin-induced airway hyperresponsiveness in Brown Norway rats. The 20th Joint Annual Conference of Biomedical Science, Taipei, Taiwan.
20. Sun, T. B., C. C. H. Yang, C. J. Lai, and T. B. J. Kuo. (2005) Cardiovascular neural regulation in response to acute programmed intermittent apnea. The 20th Joint Annual Conference of Biomedical Science, Taipei, Taiwan.
21. Yen, Y. P. and C. J. Lai. (2004) Effects of adenosine on sleep apneas in rats. The 19th Joint Annual Conference of Biomedical Science, Taipei, Taiwan.
22. Hsu, Y. Y., T. B. J. Kuo, C. C. H. Yang, and C. J. Lai. (2004) Blood pressure response to intermittent hypoxia in rats: roles of autonomic nervous functions, The 19th Joint Annual Conference of Biomedical Science, Taipei, Taiwan.
23. Lai, C. J. and P. N. Chuang. (2003) Role of arterial chemoreceptors in sleep apneas in rats. The 18th Joint Annual Conference of Biomedical Science, Taipei, Taiwan.
24. Yau, S. Y. and C. J. Lai. Hydralazine and CGS21680 modulate the incidence of sleep apneas in SHR. (2003) The 18th Joint Annual Conference of Biomedical Science, Taipei, Taiwan.
25. Lai, C. J. and H. F. Chen. (2002) Effects of acetazolamide on sleep-related apnea in rats. The 17th Joint Annual Conference of Biomedical Science, Taipei, Taiwan.
26. Lai, C. J. and Y. R. Kou. (2001) Role of cyclooxygenase products in the stimulation of pulmonary C fibers and irritant receptors by endotoxin in rats. The 16th Joint Annual Conference of Biomedical Science, Taipei, Taiwan.
27. Lai, C. J. and Y. R. Kou. (2000) Effects of endotoxin on the discharge of lung vagal sensory receptors in rats. Experimental Biology 2000, San Diego, USA.
28. Lai, C. J. and Y. R. Kou. (2000) Effects of endotoxin on the discharge of lung vagal sensory receptors in rats. The 15th Joint Annual Conference of Biomedical Science, Taipei, Taiwan.
29. Lai, C. J. and Y. R. Kou. (1998) Inhibitory effect of inhaled wood smoke on the discharge of pulmonary stretch receptors in rats. Experimental Biology 98, San Francisco, USA.
30. Hsu, T. H., C. J. Lai, and Y. R. Kou. (1996) Acute bronchoconstriction evoked by inhaled wood smoke in guinea pigs: cholinergic and noncholinergic mechanisms. The 11th Joint Annual Conference of Biomedical Science, Taipei, Taiwan.
31. Lai, C. J., T. H. Shu, and Y. R. Kou. (1996) Role of hydroxyl radical in the activation of vagal bronchopulmonary afferents by inhaled wood smoke in rats. Experimental Biology 96, Washington DC, USA.
32. Lai, C. J., T. H. Hsu, and Y. R. Kou. (1996) Role of hydroxyl radical in the activation of vagal bronchopulmonary afferents by inhaled wood smoke in rats. The 11th Joint Annual Conference of Biomedical Science, Taipei, Taiwan.
33. Lai, C. J., T. H. Shu, and Y. R. Kou. (1995) Stimulation of vagal pulmonary C-fiber afferents by inhaled wood smoke in rats. Experimental Biology 95, Atlanta, USA.
34. Kou, Y. R, C. J. Lai, C. Y. Wang, and H. C. Chang. (1995) Role of oxygen radicals in the acute ventilatory responses to inhaled wood smoke in rats. Experimental Biology 95, Atlanta, USA.
35. Chang, H. C., C. J. Lai, C. Y. Wang, and Y. R. Kou. (1995) Role of hydroxyl radicals and hydrogen peroxide in the acute ventilatory responses to inhaled wood smoke in rats. The 10th Joint Annual Conference of Biomedical Science, Taipei, Taiwan.
36. Hsu, T. H., C. J. Lai, and Y. R. Kou. (1995) Stimulatory effects of inhaled wood smoke on vagal pulmonary C-fiber afferents in rats. The 10th Joint Annual Conference of Biomedical Science, Taipei, Taiwan.
37. Lai, C. J., S. H. Yen, and J. T. Pan. (1995) Effects of natriuretic peptides and dopamine on single-unit activity of dorsomedial arcuate neurons in vitro. The 10th Annual Conference of Biomedical Science, Taipei, Taiwan.
38. Yen, S. H., C. J. Lai, and J. T. Pan. (1994) Effects of dopamine, apomorphine, and cocaine on the activity of dorsomedial arcuate neurons in rat brain slices. The 9th Joint Annual Conference of Biomedical Sciences, Taipei, Taiwan.
39. Lai, C. J. and Y. R. Kou. (1993) Acute effects on inhalation of wood smoke on breathing in rats. The 8th Joint Annual Conference of Biomedical Sciences, Taipei, Taiwan.
40. Lin, S. J., C. J. Lai, C. Y. Hong, M. S. Chang, B. N. Chiang, and S. Chien. (1991) Chronic nicotine exposure increases aortic endothelial cell death and enhances transendothelial macromolecular transport in rats. The 10th Asian Pacific Congress of Cardiology, Seoul, Korea.
專書
賴靜蓉:木屑煙影響大白鼠肺迷走感覺神經的生理機轉 國立陽明大學生理學研究所 博士論文 1998。
Full Papers
1. Liu, B. Y., T. L. Tsai, C. Y. Ho, S. H. Lu, C. J. Lai †*, Y. R. Kou †*. (2013) Role of TRPA1 and TRPV1 in the ROS-dependent sensory irritation of superior laryngeal capsaicin-sensitive afferents by cigarette smoke in anesthetized rats. Pulm Pharmacol Ther 26:364-372. (†denotes equal contribution as co-corresponding author) SCI; NSC 101-2320-B-010-042-MY3.
2. Lin, Y. J., Y. S. Lin, C. J. Lai, Z. F. Yuan, T. Ruan, and Y. R. Kou*. (2012) Perivagal antagonist treatment in rats selectively blocks the reflex and afferent responses of vagal lung C-fibers to intravenous agonists. J Appl Physiol 114: 361-370. SCI; NSC 101-2320-B-010-042-MY3 and NSC 98-2628-B-040-011-MY3
3. Shen, M. Y., Y. L. Luo, C. H. Yang, T. Ruan, and C. J. Lai*. (2012) Hypersensitivity of lung vagal C fibers induced by acute intermittent hypoxia in rats: role of reactive oxygen species and TRPA1. Am J Physiol Regul Integr Comp Physiol 303: R1175-R1185. SCI; NSC97-2320-B-320-004 and NSC98-2628-B-320-003-MY3.
4. Wang, Y. C., C. Y. Chen, T. B. J. Kuo, C. J. Lai, and C. C. H. Yang*. (2012) Influence of antipsychotic agents on heart rate variability in male WKY rats: implications for cardiovascular safety. Neuropsychobiology 65: 216-226.
5. Chen, T. I., C. J. Lai, C. J. Hsieh, K. L. Tsai, and K. T. Yang*. (2011) Differences in left ventricular cardiomyocyte loss induced by chronic intermittent hypoxia between spontaneously hypertensive and Wistar-Kyoto rats. Sleep Breath 15: 845-854. SCI; NSC-96-2320-B-320-017-MY2.
6. Lai, P. C., Y. T. Huang, C. C. Wu, C. J. Lai, P. J. Wang, T. H. Chiu*. (2011) Ceftriaxone attenuates hypoxic-ischemic brain injury in neonatal rats. J Biomed Sci 18: 69-78. SCI
7. Huang, Y. M., C. C. H. Yang, C. J. Lai, and T. B. J. Kuo*. (2011) The influence of autonomic interventions on the sleep-wake-related changes in gastric myoelectrical activity in rats. Neurogastroenterol Motil 23: 560-e208. SCI; NSC-98-2314-B-010-022.
8. Kuo, T. B. J., Z. F. Yuan, Y. S. Lin, Y. N. Lin, W. S. Li, C. C. H. Yang, and C. J. Lai*. (2011) Reactive oxygen species are the cause of the enhanced cardiorespiratory response induced by intermittent hypoxia in conscious rats. Respir Physiol Neurobiol 175: 70-79. SCI; NSC-97-2320-B-320-004 and NSC-98-2628-B-320-003-MY3.
9. Huang, Y. M., C. C. H. Yang, C. J. Lai, and T. B. J. Kuo*. (2010) Involvement of sympathetic function in the sleep-related change of gastric myoelectrical activity in rats. J Sleep Res 19: 192-200. SCI
10. Kuo, Y. L. and C. J. Lai*. (2008) Ovalbumin sensitization enhances the sensitivity of pulmonary C-fiber afferents in Brown Norway rats. J Appl Physiol 105: 611-620. SCI; NSC-92-2320-B-320-022 and NSC-93-2320-B-320-011.
11. Kuo, T. B. J., F.-Z. Shaw, C. J. Lai, and C. C. H. Yang*. (2008) Asymmetry in sympathetic and vagal activities during sleep-wake transitions. Sleep 31: 311-320. SCI; NSC-94-2314-B-010-076.
12. Lai, C. J., C. C. H. Yang, Y. Y. Hsu, Y. N. Lin, and T. B. J. Kuo*. (2006) Enhanced sympathetic outflow and decreased baroreflex sensitivity are associated with intermittent hypoxia-induced systemic hypertension in conscious rats. J Appl Physiol 100: 1974-1982. SCI; NSC-94-2320-B-320-007.
13. Sun, T. B., C. C. H. Yang, C. J. Lai, and T. B. J. Kuo*. (2006) Time course of cardiovascular neural regulation during programmed 20-sec apnea in rats. Crit Care Med 34: 765-770. SCI; NSC-92-2314-B-303-013.
14. Kuo, T. B. J.,†C. J. Lai,†Y. T. Huang, and C. C. H. Yang*. (2005) Regression analysis between heart rate variability and baroreflex-related vagus nerve activity in rats. J Cardiovasc Electrophysiol 16: 864-869. SCI; NSC-93-2320-B-320-008. (†denotes equal contribution as co-first author)
15. Chen, H. Y., T. B. J. Kuo, F.-Z. Shaw, C. J. Lai, and C. C. H. Yang*. (2005) Sleep-related vagotonic effect of zolpidem in rats. Psychopharmacology (Berl) 181: 270-279. SCI; NSC-93-2314-B-320-008.
16. Lai, C. J., T. Ruan, and Y. R. Kou*. (2005) The involvement of hydroxyl radical and cyclooxygenase metabolites in the activation of lung vagal sensory receptors by circulatory endotoxin in rats. J Appl Physiol 98: 620-628. SCI; NSC-92-2320-B-010-025, NSC-92-2320-B-010-038, NSC-91-2320-B-320-005, and NSC-89-2320-B-320-021.
17. Kuo, T. B. J., F.-Z. Shaw, C. J. Lai, C.-W. Lai, and C. C. H. Yang*. (2004) Changes in sleep patterns in spontaneously hypertensive rats. Sleep 27: 406-412. SCI; NSC-90-2745-P320-001 and NSC-91-2320-B320-007.
18. Kuo, T. B. J., C. J. Lai, F.-Z. Shaw, C.-W. Lai, and C. C. H. Yang*. (2004) Sleep-related sympathovagal imbalance in SHR. Am J Physiol Heart Circ Physiol 286: H1170-1176. SCI; NSC-90-2745-P320-001.
19. Yang, C. C. H., F.-Z. Shaw, C. J. Lai, C.-W. Lai, and T. B. J. Kuo*. (2003) Relationship between electroencephalogram slow-wave magnitude and heart rate variability during sleep in rats. Neurosci Lett 336: 21-24. SCI; NSC-89-2745-P320-001 and NSC-89-2320-B320-026.
20. Shaw, F. Z.,* C. J. Lai, and T. H. Chiu. (2002) A low-noise flexible integrated system for recording and analysis of multiple electrical signals during sleep-wake states in rats. J Neurosci Methods 118: 77-87.
21. Lai, C. J., C. Y. Ho and Y. R. Kou*. (2002) Activation of lung vagal sensory receptors by circulatory endotoxin in rats. Life Sci 70: 2125-2138.
22. Lai, C. J. and Y. R. Kou*. (1998) Inhibitory effect of inhaled wood smoke on the discharge of pulmonary stretch receptors in rats. J Appl Physiol 84: 1138-1143.
23. Lai, C. J. and Y. R. Kou*. (1998) Stimulation of pulmonary rapidly adapting receptors by inhaled wood smoke in rats. J Physiol 508: 597-607.
24. Lai, C. J. and Y. R. Kou*. (1998) Stimulation of vagal pulmonary C fibers by inhaled wood smoke in rats. J Appl Physiol 84: 30-36.
25. Yen, S. H., C. J. Lai, J. Y. Lin, and J. T. Pan*. (1997) Inhibitory effect of dopamine on dorsomedial arcuate neurons in rat brain slices: potentiation by coadministration of cocaine. Brain Res Bull 42: 347-3517.
26. Kou, Y. R.*, C. J. Lai, T. H. Hsu, and Y. S. Lin. (1997) Involvement of hydroxyl radical in the immediate ventilatory responses to inhaled wood smoke in rats. Respir Physiol 107: 1-13.
27. Pan, J. T.*, C. J. Lai, and S. H. Yen. (1996) Effects of natriuretic peptides and dopamine on single-unit activity of dorsomedial arcuate neurons in rat brain slices. Brain Res 737: 78-82.
28. Wang, C. Y., C. J. Lai, and Y. R. Kou*. (1996) Inhibitory influence of lung vagal C-fiber afferents on the delayed ventilatory response to inhaled wood smoke in rats. Chinese J Physiol 39: 15-22.
29. Kou, Y. R.*, C. Y. Wang, and C. J. Lai. (1995) Role of vagal afferents in the acute ventilatory responses to inhaled wood smoke in rats. J Appl Physiol 78: 2070-2078.
30. Kou, Y. R.* and C. J. Lai. (1994) Reflex changes in breathing pattern evoked by inhalation of wood smoke in rats. J Appl Physiol 76: 2333-2341.
Conference Abstracts
1. Yang, C. H., Y. R. Kou, M. C. Liang, and C. J. Lai. (2013) Effect of reactive oxygen species on hypersensitivity of lung vagal C fibers induced by intermittent hypoxia in rats. The 12th meeting of the Asia Pacific Federation of Pharmacologists, Shanghai, China.
2. Lin, T. Y. and C. J. Lai. (2013) Effect of intermittent hypoxia on airway hyperresponsiveness in Brown Norway rats. Symposia, the 28th Joint Annual Conference of Biomedical Science, Taipei, Taiwan.
3. Lai, C. J., M. Y. Shen, Y. L. Luo, and C. H. Yang. (2012) Hypersensitivity of lung vagal C fibers induced by acute intermittent hypoxia in rats: role of reactive oxygen species and TRPA1. Experimental Biology 2012, San Diego, USA.
4. Jian, L. Y. and C. J. Lai. (2011) Hypersensitivity of pulmonary chemoreflex induced by exercise: role of reactive oxygen species and cyclooxygenase metabolites. Symposia, the 26th Joint Annual Conference of Biomedical Science, Taipei, Taiwan.
5. Shen, M.-Y., Y.-L. Luo, and C. J. Lai. (2010) Intermittent hypoxia enhances chemical sensitivity of pulmonary C fibers in rats: role of reactive oxygen species. Experimental Biology 2010, Anaheim, USA.
6. Li, W. S., T. B. J. Kuo, C. C. H. Yang, and C. J. Lai. (2010) Effect of N-acetylcysteine on intermittent hypoxia-enhanced cardiorespiratory response in conscious normotensive and hypertensive rats. Symposia, the 25th Joint Annual Conference of Biomedical Science, Taipei, Taiwan.
7. Zhuang, W. L. and C. J. Lai. (2010) Chronic intermittent hypoxia enhances sensitivity of pulmonary C fibers in rats. Symposia, the 25th Joint Annual Conference of Biomedical Science, Taipei, Taiwan.
8. Yuan, Z. F., M.-J. Lin, T. B. J. Kuo, C. C. H. Yang, and C. J. Lai. (2009) Role of superoxide anion in the chemoreflex and cardiovascular responses to chronic intermittent hypoxia in spontaneously hypertensive rats. 36th International Congress of Physiological Sciences, Kyoto, Japan.
9. C.-H. Yang, T. B. J. Kuo, C. C. H. Yang, and C. J. Lai. (2009) Inducible nitric oxide synthase contributes to chronic intermittent hypoxia-induced chemoreflex activation and cardiovascular responses in spontaneously hypertensive rats. Symposia, the 24th Joint Annual Conference of Biomedical Science, Taipei, Taiwan.
10. Lai, C. J., Y.-N. Lin, T. B. J. Kuo, and C. C. H. Yang. (2008) Role of reactive oxygen species in the chemoreflex and cardiovascular responses to intermittent hypoxia in conscious rats. 2008 ATS International Conference, Toronto, Canada.
11. Luo, Y.-L., Y.-J. Chen, and C. J. Lai. (2008) Neuroplasticity of pulmonary C fibers induced by intermittent hypoxia in rats. Symposia, the 23th Joint Annual Conference of Biomedical Science, Taipei, Taiwan.
12. Lin, M.-J., T. B. J. Kuo, C. C. H. Yang, and C. J. Lai. (2008) Exaggerated blood pressure response to intermittent hypoxia is associated with enhanced arterial chemoreflex sensitivity and sympathetic outflow in spontaneously hypertensive rats. The 23th Joint Annual Conference of Biomedical Science, Taipei, Taiwan.
13. Lai, C. J., J.-Z. Deng, C. C. H. Yang, and T. B. J. Kuo (2007) Cardiorespiratory changes evoked by chronic intermittent hypoxia in female rats: role of estrogen. International Brain Research Organization (IBRO) 2007 Congress Satellite Meeting, S11 Physiology and Pathophysiology of the Autonomic Nervous System, Hualien, Taiwan.
14. Deng, J.-Z., C. C. H. Yang, T. B. J. Kuo, and C. J. Lai. (2007) Endogenous sex steroids in the chemoreflex and cardiovascular responses to chronic intermittent hypoxia in conscious rats. The 22th Joint Annual Conference of Biomedical Science, Taipei, Taiwan.
15. Chen, Y.-J., Y.-N. Lin, T. B. J. Kuo, C. C. H. Yang, and C. J. Lai. (2007) Role of hydroxyl radical in the chemoreflex and cardiovascular responses to chronic intermittent hypoxia in conscious rats. The 22th Joint Annual Conference of Biomedical Science, Taipei, Taiwan.
16. Lai, C. J., Y.-N. Lin, T. B. J. Kuo, and C. C. H. Yang. (2006) Intermittent hypoxia enhances chemoreflex sensitivity and sympathetic activity in conscious rats: roles of reactive oxygen species. The Fourth Symposium on Hypoxia across the Strait. The Eighth Chiang Shou-Teh Symposium, Taipei and Hualien, Taiwan.
17. Lin, Y.-N., T. B. J. Kuo, C. C. H. Yang, and C. J. Lai. (2006) Role of superoxide anion in the chemoreflex and cardiovascular responses to chronic intermittent hypoxia in conscious rats. The 21th Joint Annual Conference of Biomedical Science, Taipei, Taiwan.
18. Lai, C. J., C. C. H. Yang, Y. Y. Hsu, and T. B. J. Kuo. (2005) Enhanced sympathetic activity and decreased baroreflex sensitivity are associated with intermittent hypoxia-induced systemic hypertension in conscious rats. 2005 ATS International Conference, San Diego, USA.
19. Kuo, Y. L. and C. J. Lai. (2005) The involvement of pulmonary C fibers in ovalbumin-induced airway hyperresponsiveness in Brown Norway rats. The 20th Joint Annual Conference of Biomedical Science, Taipei, Taiwan.
20. Sun, T. B., C. C. H. Yang, C. J. Lai, and T. B. J. Kuo. (2005) Cardiovascular neural regulation in response to acute programmed intermittent apnea. The 20th Joint Annual Conference of Biomedical Science, Taipei, Taiwan.
21. Yen, Y. P. and C. J. Lai. (2004) Effects of adenosine on sleep apneas in rats. The 19th Joint Annual Conference of Biomedical Science, Taipei, Taiwan.
22. Hsu, Y. Y., T. B. J. Kuo, C. C. H. Yang, and C. J. Lai. (2004) Blood pressure response to intermittent hypoxia in rats: roles of autonomic nervous functions, The 19th Joint Annual Conference of Biomedical Science, Taipei, Taiwan.
23. Lai, C. J. and P. N. Chuang. (2003) Role of arterial chemoreceptors in sleep apneas in rats. The 18th Joint Annual Conference of Biomedical Science, Taipei, Taiwan.
24. Yau, S. Y. and C. J. Lai. Hydralazine and CGS21680 modulate the incidence of sleep apneas in SHR. (2003) The 18th Joint Annual Conference of Biomedical Science, Taipei, Taiwan.
25. Lai, C. J. and H. F. Chen. (2002) Effects of acetazolamide on sleep-related apnea in rats. The 17th Joint Annual Conference of Biomedical Science, Taipei, Taiwan.
26. Lai, C. J. and Y. R. Kou. (2001) Role of cyclooxygenase products in the stimulation of pulmonary C fibers and irritant receptors by endotoxin in rats. The 16th Joint Annual Conference of Biomedical Science, Taipei, Taiwan.
27. Lai, C. J. and Y. R. Kou. (2000) Effects of endotoxin on the discharge of lung vagal sensory receptors in rats. Experimental Biology 2000, San Diego, USA.
28. Lai, C. J. and Y. R. Kou. (2000) Effects of endotoxin on the discharge of lung vagal sensory receptors in rats. The 15th Joint Annual Conference of Biomedical Science, Taipei, Taiwan.
29. Lai, C. J. and Y. R. Kou. (1998) Inhibitory effect of inhaled wood smoke on the discharge of pulmonary stretch receptors in rats. Experimental Biology 98, San Francisco, USA.
30. Hsu, T. H., C. J. Lai, and Y. R. Kou. (1996) Acute bronchoconstriction evoked by inhaled wood smoke in guinea pigs: cholinergic and noncholinergic mechanisms. The 11th Joint Annual Conference of Biomedical Science, Taipei, Taiwan.
31. Lai, C. J., T. H. Shu, and Y. R. Kou. (1996) Role of hydroxyl radical in the activation of vagal bronchopulmonary afferents by inhaled wood smoke in rats. Experimental Biology 96, Washington DC, USA.
32. Lai, C. J., T. H. Hsu, and Y. R. Kou. (1996) Role of hydroxyl radical in the activation of vagal bronchopulmonary afferents by inhaled wood smoke in rats. The 11th Joint Annual Conference of Biomedical Science, Taipei, Taiwan.
33. Lai, C. J., T. H. Shu, and Y. R. Kou. (1995) Stimulation of vagal pulmonary C-fiber afferents by inhaled wood smoke in rats. Experimental Biology 95, Atlanta, USA.
34. Kou, Y. R, C. J. Lai, C. Y. Wang, and H. C. Chang. (1995) Role of oxygen radicals in the acute ventilatory responses to inhaled wood smoke in rats. Experimental Biology 95, Atlanta, USA.
35. Chang, H. C., C. J. Lai, C. Y. Wang, and Y. R. Kou. (1995) Role of hydroxyl radicals and hydrogen peroxide in the acute ventilatory responses to inhaled wood smoke in rats. The 10th Joint Annual Conference of Biomedical Science, Taipei, Taiwan.
36. Hsu, T. H., C. J. Lai, and Y. R. Kou. (1995) Stimulatory effects of inhaled wood smoke on vagal pulmonary C-fiber afferents in rats. The 10th Joint Annual Conference of Biomedical Science, Taipei, Taiwan.
37. Lai, C. J., S. H. Yen, and J. T. Pan. (1995) Effects of natriuretic peptides and dopamine on single-unit activity of dorsomedial arcuate neurons in vitro. The 10th Annual Conference of Biomedical Science, Taipei, Taiwan.
38. Yen, S. H., C. J. Lai, and J. T. Pan. (1994) Effects of dopamine, apomorphine, and cocaine on the activity of dorsomedial arcuate neurons in rat brain slices. The 9th Joint Annual Conference of Biomedical Sciences, Taipei, Taiwan.
39. Lai, C. J. and Y. R. Kou. (1993) Acute effects on inhalation of wood smoke on breathing in rats. The 8th Joint Annual Conference of Biomedical Sciences, Taipei, Taiwan.
40. Lin, S. J., C. J. Lai, C. Y. Hong, M. S. Chang, B. N. Chiang, and S. Chien. (1991) Chronic nicotine exposure increases aortic endothelial cell death and enhances transendothelial macromolecular transport in rats. The 10th Asian Pacific Congress of Cardiology, Seoul, Korea.
專書
賴靜蓉:木屑煙影響大白鼠肺迷走感覺神經的生理機轉 國立陽明大學生理學研究所 博士論文 1998。